The following are sister cities of Santa Cruz: * Alushta, Ukraine * Jinotepe, Nicaragua * Puerto La Cruz, Venezuela * Sestri Levante, Italy * Shingu, Japan

The City of Santa Cruz Sister Cities Committee works to strengthen relationships through a variety of activities such as: * Humanitarian projects abroad * Youth programs/exchanges * Visitor exchanges * Cultural and business exchanges * School affiliations/pen pals (adult & children) * Hospitality Committee for greeting foreign visitors * Local projects benefiting Santa Cruz * Friendship garden on the mall in downtown Santa Cruz